HIV & AIDS
AIDS (Acquired Immune Deficiency Syndrome) is caused by the Human Immunodeficiency Virus (HIV).  Over time, the HIV virus weakens the immune system by infecting and killing certain white blood cells.  It is only after the immune system is significantly weakened that people with HIV get one or more "opportunistic" infections. Before this happens, there are essentially no symptoms or signs that indicate that somebody is infected with HIV. Magic Johnson has become an unofficial spokesman for this disease. A vigorous and healthy man living with HIV, he got infected through heterosexual intercourse and now is a major force in educating people about this disease.

It often takes many many years for somebody infected with HIV to have their immune system weakened to the point where these opportunistic infections (and unusual cancers) can occur.  Once somebody begins to get these infections, they are said to have AIDS.

The disease was first defined by the CDC (Centers for Disease Control & Prevention) in 1981.   It is estimated that over a million Americans are infected with HIV (one in every 250 people).  Over 20 million people are infected worldwide.  In some areas of Africa, 1 out of every 2 people have HIV!  Though this disease was first thought to infect only homosexuals and IV drug users who share needles, it has since become clear that anybody exchanging bodily fluids (e.g., blood, semen, vaginal secretions, and possibly even saliva) can get this infection.  Most of the continual spread of HIV is caused by unprotected heterosexual sex, followed by homosexual sex, IV drug use, and transmission to a baby by an infected mother.


Early HIV diagnosis and entry into health care system have both individual and societal benefits: improved health and productivity, reduced hospitalization costs, and decreased transmission from persons who do not know their HIV status.
First, those who learn of their infection can take steps to avoid infecting others.  Second, early treatment with new anti-viral medicines can slow the progression of the disease.  Third, many of the opportunistic diseases can be prevented before they occur by using antibiotics and other medicines.

Early diagnosis of HIV is absolutely critical, so getting tested by your doctor is important if you have any risk factors, including a history of sharing needles, a history of unprotected heterosexual intercourse, if you are a man who has sex with men, or if you had a blood transfusion prior to 1987. Only blood, semen, vaginal fluid, breast milk, other body fluids containing blood, have been proven to spread HIV. (It is felt to be particularly unlikely that one can catch HIV through contact with saliva) You don't catch HIV from talking to, working with, shaking hands, hugging, or kissing people who have HIV or AIDS! 

A huge amount of ongoing research is being done to find a vaccine to prevent non-infected people from getting HIV if exposed, as well as finding better treatments and cures for those already infected.  Though excellent and continually improving treatment is prolonging life and slowing the course of this disease, HIV infection is still considered to be nearly 100% fatal (even the Ebola virus isn't that vicious)!

Kaposi's sarcoma on the trunk and leg of a patient with AIDS

Common Signs & Symptoms
The signs & symptoms of HIV and AIDS are very different depending on how damaged ones immune system has become.  When somebody initially gets exposed and infected by HIV, they often have flu-like symptoms (fever, chills, feeling lousy, swollen glands, etc.).  These symptoms go away, and most people have no idea they have this infection until they are diagnosed with a blood test or they develop an opportunistic infection or unusual cancer. 

The most common opportunistic infections include, Candida albicans (caused by a fungus) throat and body infection, Pneumocystis carinii (caused by a bacteria) pneumonia, Toxoplasmosis (caused by a fungus) brain infection, Cryptococcus (fungus) brain and body infection, Tuberculosis (bacteria) lung and body infection, Cytomegalovirus (CMV, virus) eye and body infection.  The most common cancer associated with AIDS is called Kaposi's sarcoma.  Many other infections (such as Herpes, HPV, Streptococcal pneumonia, and Salmonella) occur in people with AIDS.

Throat infection with Candida albicans (thrush)

Oral Leukoplakia 

How's it Diagnosed?
Diagnosis is made by a blood test that finds antibodies against HIV (meaning you have been exposed to the virus and your body has developed an immune response and is making antibodies in an attempt to fight off the infection).  Many times, people first learn they have AIDS when they go to their doctor with one of the common opportunistic infections or Kaposi's sarcoma.

How's it Treated?
Currently there is no cure for HIV infection.  Treatment is geared towards both controlling the virus and treating the opportunistic infections.  Many new and exciting anti-viral medications have had good success in slowing down the progression of HIV infection by preventing the virus from multiplying.  Medications such as AZT, ddI, ddC, and the newer protease-inhibitors have gotten a lot of press since HIV was defined.  Newer, less toxic, and better medications are continually being introduced and even more are on the way.  Vaccine studies are underway both for those uninfected (i.e., the general population) and those already infected (to boost the immune system).  Taking good care of oneself (eating healthily, exercising, etc.) also seems crucial in preventing the rapid progression of HIV.   Pregnant women who have HIV infection should be treated with medicine during their pregnancy AND at delivery as this has been clearly proven to markedly reduce the rate of transmitting the infection to the baby.

How do I avoid Getting It  (Prevention)?
Avoiding exposure to bodily fluids (blood, semen, vaginal secretions, etc.) is the surest way to avoid getting HIV.  Abstinence or correct condom use with a latex condom will prevent transmission of HIV from one person to the next.   Pregnant women who have HIV infection should be treated with medicine during their pregnancy AND at delivery to minimize the risk of spreading it to their baby.

Additional Information
A terrific site for information on HIV and AIDS is called aidsmap. Get additional information on this and other diseases by clicking here.

 

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